Phase III COMPASS study of Xarelto stopping early for 'overwhelming efficacy'

9 February 2017
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The Phase III trial COMPASS evaluating the efficacy and safety of Xarelto (rivaroxaban) for the prevention of major adverse cardiac events (MACE) including cardiovascular death, myocardial infarction and stroke in patients with coronary artery disease (CAD) or peripheral artery disease (PAD) has met its primary endpoint ahead of time.

Blood thinner Xarelto was discovered by Germany’s Bayer (BAYN: DE) and is marketed in the USA with its cooperation partner Janssen Research & Development, a unit of US healthcare giant Johnson & Johnson (NYSE: JNJ). The drug generated third-quarter 2016 sales of 571 million euros ($611.5 million) for Bayer. According to J&J’s recently-reported financials, Xarelto had sales of $2.29 billion in 2016.

Bayer’s shares gained 2.23% to 105.35 euros in late-morning trading today.

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