Overall safety of measles-mumps-rubella-varicella vaccine confirmed by 12-year study
A 12-year study published in the journal Pediatrics has confirmed the safety of two measles-containing vaccines. Seven main adverse outcomes were found to be unlikely after either vaccine.
The study was carried out at the Kaiser Permanente Vaccine Study Center and examined children aged 12 to 23 months between January 2000 and June 2012, who received measles-mumps-rubella-varicella (MMRV) or separately-administered same-day measles-mumps-rubella and varicella (or MMR + V) vaccines. A total of 123,200 MMRV doses and 584,987 MMR + V doses were evaluated.
No increased risk of the seven main neurological, blood or immune system disorders was found in either arm, and no new safety concerns were identified after either vaccine. Most outcomes studied were unlikely after either vaccine.
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