Otsuka inks deal for investigational cancer drug

16 December 2016

Japanese drug major Otsuka Pharmaceutical (TYO: 4578) has entered into an exclusive license agreement for the joint development and commercialization in Japan of the investigational oncolytic virus HF10 therapy (HF10) for the treatment of pancreatic cancer, melanoma and other tumors developed by Takara Bio (TYO: 4974).

HF10 is an attenuated strain of Herpes simplex virus type 1 (HSV-1), an oncolytic virus which in clinical trials to date has demonstrated antitumor activity when injected into cancerous areas. Oncolytic viruses, which rarely proliferate in normal cells, destroy cancer cells directly by proliferating inside them.

Deal worth up to 3 billion yen

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