Orion leaps on news of MSD deal for ODM-208 in prostate cancer

13 July 2022

Shares of Finnish drugmaker Orion Corporation (Nasdaq OMX: ORNAV) jumped 7.6% to 47.60 euros by mid-morning, as it announced an important collaboration with US pharma giant Merck & Co (NYSE: MRK), which operates under the MSD name outside of the USA and Canada.

The companies have signed a global development and commercialization agreement for Orion’s investigational candidate ODM-208 and other drugs targeting cytochrome P450 11A1 (CYP11A1), an enzyme important in steroid production. ODM-208 is an oral, non-steroidal inhibitor of CYP11A1 currently being evaluated in a Phase II clinical trial for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC).

Terms of the accord

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