Semaglutide posts strong trial performance, generating blockbuster buzz

20 August 2018

Novo Nordisk (NOV: N) announced on Monday that its type 2 diabetes therapy oral semaglutide had met its targets in the Phase IIIa PIONEER-5 trial, showing itself to be more effective than placebo in reducing blood sugar and weight.

Semaglutide, under the trade name Ozempic, is widely available to type 2 diabetes patients in the form of a weekly injection, and has proven itself to be more effective in aiding weight loss than Eli Lilly's (NYSE: LLY) Trulicity (dulaglutide).

"The results from PIONEER-5 showed that oral semaglutide is efficacious and has a solid safety profile in people with type 2 diabetes and moderate renal impairment, thereby further expanding the solid clinical profile of oral semaglutide," said Mads Krogsgaard Thomsen, executive vice president and chief science officer of Novo Nordisk.

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