Ono to test Opdivo / Rubraca combination in key Asian countries

28 August 2018

Osaka, Japan-based Ono Pharmaceutical (TYO: 4528) and its development partner Bristol-Myers Squibb (NYSE: BMY) have agreed a deal with Clovis Oncology (Nasdaq: CLVS) to test a combination of Opdivo (nivolumab) and Rubraca (rucaparib) in multiple tumor types.

The trials will see Ono and Bristol-Myers’ flagship checkpoint inhibitor and Clovis’ PARP inhibitor tested against ovarian cancer, breast cancer and prostate cancer in Japan, South Korea and Taiwan.

Clovis, which has received approvals for Rubraca in multiple recurrent ovarian cancer settings in the USA and Europe, is conducting both monotherapy and combination development programs to extend the marketable uses of the drug.

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