Onivyde could become first-line standard of care in pancreatic cancer

23 January 2023
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French drugmaker Ipsen (Euronext: IPN) has presented positive results from the Phase III NAPOLI 3 study of Onivyde (irinotecan) in metastatic pancreatic ductal adenocarcinoma (mPDAC).

The trial is testing the NALIRIFOX regimen of Onivyde plus leucovorin and oxaliplatin, in comparison with a chemotherapeutic treatment of nab-paclitaxel plus gemcitabine.

The results show the trial met its primary endpoint, with improved overall survival (OS) and progression-free survival (PFS) for the test group, after a median follow-up of 16.1 months.

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