Novo Nordisk releases positive new data from Phase IIIa semaglutide study

18 December 2015

Danish diabetes care giant Novo Nordisk (NOV: N) has announced the headline results from the fourth Phase IIIa trial for semaglutide, SUSTAIN2. Semaglutide is a new GLP-1 analogue administered subcutaneously once weekly.

The double-blinded trial investigated the efficacy and safety of 0.5mg and 1.0mg semaglutide compared with 100mg sitagliptin, a once-daily DPP-IV inhibitor, after 56 weeks of treatment in 1,231 people with type 2 diabetes, where both drugs were added on to metformin, thiazolidinedione (TZD) or a combination of metformin/TZD.

Market potential

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