Novel oral anticoagulants require improved safety data to challenge warfarin; Report

29 September 2015

More real-world safety data, especially in patients with a high risk of cardiovascular disease, could potentially address the issue of under-dosing and under-treatment with novel oral anticoagulants (NOACs) in global practice, says an analyst.

According to Dr Lakshmi Dharmarajan, research and consulting firm GlobalData's senior analyst covering cardiovascular and metabolic disorders, while the underutilization of NOACs is a commonly acknowledged issue due to the approved lower doses of these drugs in the US, this could change with the launch of new NOAC antidotes in the near future.

Antidotes under development

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