Japanese mid-size drugmaker Nippon Shinyaku (TYO: 4526) and the local subsidiary of global pharma behemoth Pfizer (NYSE: PFE) have concluded an exclusive sales promotion consignment contract in Japan for Tramal Capsule (tramadol hydrochloride), a cancer pain and chronic pain treatment for which Nippon Shinyaku holds the marketing rights, as well as NS-24 (once-daily tramadol hydrochloride), a new treatment under development by Nippon Shinyaku for the same indications.
According to this contract, Nippon Shinyaku will commission Pfizer with the exclusive sales promotion of Tramal and NS-24. While Pfizer becomes a single sales promoter as of December 1, 2013, Nippon Shinyaku will continue to act as a distributor.
Tramal is a non-narcotic opioid analgesic which acts as μ-opioid receptor agonist and monoaminergic action (reuptake inhibition of noradrenaline and serotonin), which Nippon Shinyaku launched in Japan in September 2010.
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