NICE U-turn on Cabometyx for advanced renal cell cancer

10 July 2017

In a reversal of a negative draft guidance in February, the medicines cost-effectiveness watchdog for England and Wales has today issued final guidance recommending cabozantinib for some kidney cancer patients.

The drug is marketed in Europe by French drugmaker Ipsen (Euronext: IPN) under the trade name Cabometyx, under license from USA-based biotech firm Exelixis (Nasdaq: EXEL).

The National Institute for Health and Clinical Excellence’ s (NICE) independent appraisal committee had previously found the additional benefits of cabozantinib, compared with current care, were not sufficient to justify the cost of treatment. There was also uncertainty about which medicines cabozantinib should be compared with. This meant NICE could not recommend the drug.

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