Missing data to prove that a combination involving Ninlaro (ixazomib) prolongs overall survival in relapsed or refractory (R/R) multiple myeloma (MM) compared with the current treatment has added further delay to National Health Service (NHS) funding for patients in England and Wales.
Japanese pharma major Takeda (TYO: 4502) has expressed frustration at the decision of the National Institute for Health and Care Excellence (NICE) to issue a second negative appraisal consultation document (ACD) for ixazomib in combination with lenalidomide and dexamethasone (IRd), for the treatment of patients who have received one or more previous therapies.
"CDF is supposed to provide access to innovative cancer drugs while further clinical evidence is gathered and used to demonstrate that these drugs are cost-effective – Takeda is collecting this data for ixazomib"
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