AstraZeneca (LSE: AZN) says that the National Institute of Health and Care Excellence (NICE) has today published a Technology Appraisal Guidance (TAG) recommending Daxas (roflumilast) for use within NHS England as an add-on option to treat adults with severe chronic obstructive pulmonary disease (COPD) who continue to experience exacerbations despite triple inhaled therapy.
Roflumilast, as an add-on to bronchodilator therapy, is now recommended by the medicines cost-effectiveness watchdog NICE within its marketing authorization as an option to treat severe COPD in adults with chronic bronchitis only if:
1) the disease is severe, defined as a forced expiratory volume in 1 second (FEV1) after a bronchodilator of less than 50% of predicted normal, and
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