NICE recommends first treatment for acute migraine

14 September 2023

UK health technology assessor the National Institute for Health and Care Excellence (NICE) has issued final draft guidance that recommends US pharma giant Pfizer’s (NYSE: PFE) Vydura (rimegepant) as an option for the acute treatment of migraine with or without aura in adults, only if for previous migraines:

at least 2 triptans were tried and they did not work well enough or
triptans were contraindicated or not tolerated, and nonsteroidal anti-inflammatory drugs (NSAIDs) and paracetamol were tried but did not work well enough.

The drug was developed by Biohaven Pharmaceuticals, which Pfizer acquired in an $11.6 billion deal, and is commercialized as Nurtec ODT in the USA. Vydura was approved in the European Union in April 2022.

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