NICE nod for AstraZeneca drug in HFrEF

7 January 2021
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The UK National Institute for Health and Care Excellence (NICE) has issued a positive Final Appraisal Document (FAD) recommending Forxiga (dapagliflozin) for symptomatic chronic heart failure (HF) with reduced ejection fraction (HFrEF) in adults, as an add-on to optimised standard care.

NICE, the cost-effectiveness watchdog for England and Wales, recommends that treatment with the AstraZeneca (LSE: AZN) drug is started on the advice of a heart failure specialist, and that monitoring should be done by the most appropriate healthcare professional.

Forxiga, which is also branded as Farxiga, is in a class of drugs called SGLT2 inhibitors, and is the first medicine of this kind to be licensed and recommended for use in HF.

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