NICE extends guidance to include new recommendation for Bayer's Xofigo

29 September 2016

The National Institute for Health and Care Excellence (NICE) has published final guidance recommending German pharma major Bayer’s (BAYN: DE) Xofigo (radium-223 dichloride) for a new indication in prostate cancer.

NICE, the medicines cost-effectiveness watchdog for England and Wales, has added a further recommendation for Xofigo, to treat men with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastases where docetaxel is contraindicated or is not suitable.

In previous guidance, Xofigo was not recommended for people for whom docetaxel was not suitable, though the NICE performed a U-turn on this after receiving an updated cost-effectiveness analyses comparing radium-223 with the current care available for people in this patient group.

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