NGM Biopharma in deal with Janssen for novel diabetes therapeutics; Microbiotix in-licenses drugs from Merck & Co

4 January 2013

USA-based NGM Biopharmaceuticals has signed a worldwide agreement with health care giant Johnson & Johnson (NYSE: JNJ) subsidiary Janssen Pharmaceuticals to discover and develop novel therapeutics for the potential treatment of type 2 diabetes and other metabolic diseases.

NGM and Janssen will jointly conduct research on selected protein factors discovered by NGM using its diabetes discovery platform, with the goal of advancing drug candidates that mimic the potential glucoregulatory effects of bariatric surgery on diabetes patients. Janssen will receive an exclusive worldwide license to develop, manufacture and commercialize compounds resulting from the collaboration.

Under the deal, NGM will receive an upfront payment and research support for activities conducted in collaboration with Janssen. In addition, NGM is eligible to receive payments on the achievement of certain research, development, regulatory and commercial milestones, as well as royalties on worldwide product sales. Further terms were not disclosed.

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