Next-gen BTK blocker offers fightback against drug resistance

13 December 2022

Eli Lilly’s (NYSE: LLY) oncology company, Loxo@Lilly, has announced updated clinical data from the global Phase I/II BRUIN trial of pirtobrutinib.

At the annual meeting of the American Society of Hematology (ASH), Lilly is presenting data on the safety and efficacy of the therapy in various blood cancers including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL) and mantle cell lymphoma (MCL).

The significantly longer follow-up data show continued benefit for a pre-treated group of people with B-cell malignancies, for whom there are very few options remaining.

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