Swiss drugmaker Arvelle Therapeutics has published positive results from a key pivotal trial for the in-licensed candidate cenobamate.
The CNS disorder specialist said the trial showed significant improvements in seizure control for partial-onset (focal) seizures in adults with epilepsy.
Responder rates were 40%, 56% and 64% at the three dosage levels, compared to 25% for placebo. During the maintenance phase of the study, zero seizures were reported by 4%, 11% and 21% of the respective groups, compared with 1% for placebo.
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