In Alzheimer's, most of the focus has been on the newly-emerging class of intravenous biologics for early-stage disease, and the potential for subcutaneous versions to widen access and improve the patient experience.
One privately-held American company hopes to go one better.
As the name suggests, Alzheon is a specialist in this disease, and the firm is betting on a different mechanism of action to unlock the holy grail for scientists studying Alzheimer's - a disease-modifying pill.
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