New kind of targeted cancer drug available at last in Europe

11 May 2023

French drugmaker Servier has secured European approval for Tibsovo (ivosidenib) in two indications, making it the first and only IDH1 blocker to be available in the region.

In recent years, scientists have noted mutations in IDH in several tumors, including glioma, acute myeloid leukemia (AML), and chondrosarcoma, leading to increased research around this target.

Originally developed by Agios Pharmaceuticals, Tibsovo has been approved in the USA since July 2018 for certain people with AML.

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