New hope for children with rare non-Hodgkin lymphoma

15 January 2021

New York-based Pfizer (NYSE: PFE) has broadened the US label for Xalkori (crizotinib), to include treatment of young adults and children over the age of 1 with anaplastic large cell lymphoma (ALCL).

The US Food and Drug Administration approval covers treatment for ALK-positive tumors, as defined by a genetic test, which have not responded well to initial treatment.

ALCL is a rare form of non-Hodgkin lymphoma which accounts for around a third of cases of NHL in young people, the vast majority of which are ALK-positive.

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