Mid-Atlantic and Accelero partner to develop USP30 blockers

5 September 2024

Mid-Atlantic BioTherapeutics (MABT) has announced a collaboration with Accelero Biostructures to identify novel inhibitors of USP30, a protein linked to neurological disorders and other conditions.

Accelero will use its proprietary ABS-OneStep platform to generate initial drug candidates, while MABT will oversee preclinical testing and further development.

USP30 plays a key role in cellular processes, particularly the removal of damaged mitochondria, opening up possibilities in treating diseases like Alzheimer's and Parkinson's.

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