Merck's HIV drugs Delstrigo and Pifeltro get FDA backing

31 August 2018

US pharma giant Merck & Co (NYSE: MRK) yesterday received approval in the USA for its fixed-dose combination HIV drug Delstrigo (doravirine/lamivudine/tenofovir disoproxil fumarate) and monotherapy Pifeltro (doravirine), around two months sooner than expected.

Both Delstrigo and Pifeltro are indicated for the treatment of HIV-1 infection in adult patients with no prior antiretroviral treatment experience, and are administered orally once daily with or without food, according to the US Food and Drug Administration approval.

Delstrigo contains a boxed warning regarding post-treatment acute exacerbation of hepatitis B (HBV) infection.Delstrigo and Pifeltro do not cure HIV-1 infection or AIDS, Merck warned.

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