Merck & Co to acquire Afferent Pharma in up to $1.25 billion deal
US pharma giant Merck & Co (NYSE:MRK) says it has signed a definite agreement to acquire privately-held US pharma firm Afferent Pharmaceuticals.
Afferent Pharmaceuticals is a leader in the development of therapeutic candidates targeting the P2X3 receptor for the treatment of common, poorly-managed, neurogenic conditions. Afferent’s lead investigational candidate, AF-219, is a selective, non-narcotic, orally-administered P2X3 antagonist currently being evaluated in a Phase IIb clinical trial for the treatment of refractory, chronic cough as well as in a Phase II clinical trial in idiopathic pulmonary fibrosis (IPF) with cough.
Deal includes $500 million upfront
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