Lyrica's limited benefit for sciatica shown by study

24 March 2017
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A blockbuster painkiller from US pharma giant Pfizer (NYSE: PFE) brings no more relief from sciatica than placebo, according to a study published in the New England Journal of Medicine

Lyrica (pregabalin) was Pfizer’s second-biggest selling drug in 2016, raising worldwide revenues of $4.17 billion. It has become the most commonly prescribed medicine for neuropathic pain but the study’s results put into doubt how effective it is when prescribed for the leg pain associated with sciatica.

"Pregabalin did not significantly reduce the intensity of leg pain associated with sciatica"

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