Long road ends in failure for bardoxolone methyl in Japan

12 May 2023

Following a regulatory update, Japanese speciality pharma company Kyowa Kirin (TYO: 4151) has announced it will pull the plug on its small molecule bardoxolone methyl.

Codenamed RTA 402, the compound was licensed from Reata Pharmaceuticals (Nasdaq: RETA), an American company, in 2009.

Reata stock has fallen around 15% since the announcement was made, but that was likely to do with a setback for its Skyclarys (omavaloxolone) announced a day earlier.

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