Lilly's ixekizumab shows superiority over etanercept and placebo in Ph III

21 August 2014

US pharma major Eli Lilly’s (NYSE: LLY) investigational medicine ixekizumab was superior to etanercept and placebo on all skin clearance measures in Phase III studies, the company said today in disclosing top-line results from its pivotal UNCOVER studies in moderate-to-severe plaque psoriasis.

In Lilly’s trials, 78% to 90% of patients treated with ixekizumab saw at least a 75% improvement in their skin clearance (PASI 75 score) at 12 weeks, and 31% to 41% saw 100% clearance (PASI 100).

Study design and results

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