Lilly's Cymbalta significantly reduced chronic low back pain in new study

5 February 2010

In a new study, 60mg of Cymbalta (duloxetine HCl) taken once daily significantly reduced chronic low back pain, as measured by the Brief Pain Inventory (BPI) average pain rating, compared with placebo.

The data were presented today at the annual meeting of the American Academy of Pain Medicine (AAPM) in San Antonio, Texas. The antidepressant Cymbalta generated sales of over $3 billion for its originator, US drug major Eli Lilly, last year (The Pharma Letter January 29).

A total of 401 patients participated in the 12-week, double-blind, placebo-controlled study, designed to assess the efficacy of duloxetine 60 mg once daily on the reduction of pain severity in patients with chronic low back pain. In the study, duloxetine-treated patients experienced a statistically significantly greater improvement on BPI average pain scale compared with placebo in chronic low back pain (p<0.005).>

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