Lilly and Boehringer present positive top-line results for Tradjenta

19 July 2018

Privately-held German firm Boehringer Ingelheim and the USA’s Eli Lilly (NYSE: LLY) have revealed positive top-line results from the CARMELINA trial studying the cardiovascular safety of Tradjenta (linagliptin) in type 2 diabetes patients.

The study met its primary endpoint, defined as time to first occurrence of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke, with similar safety for the test group compared with placebo. Both groups also received standard of care treatment.

The overall safety profile of Tradjenta, including adults with kidney disease, was consistent with previous data, and no new safety signals were observed.

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