Ligand signs deal with start-up CURx to develop first topiramate injection for epilepsy
US drugmaker Ligand Pharmaceuticals (Nasdaq: LGND) has entered a global license agreement with start-up CURx Pharmaceuticals for the development and commercialization of Ligand’s Captisol-enabled Topiramate Injection for the treatment of partial onset or primary generalized tonic-clonic seizures in hospitalized epilepsy patients who are unable to take oral topiramate.
Currently, topiramate is only available in oral formulations, and is sold by Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson (NYSE: JN), under the trade name Topamax.
Under the terms of the agreement, Ligand will be eligible to receive more than $21 million in potential net milestone payments and net royalties on future sales of 6.0% to 7.5%.
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