Letdown for Lonsurf combo in first-line colon cancer

22 October 2021

Privately-held French drugmaker Servier has announced a trial miss for its cancer med Lonsurf (trifluridine/tipiracil), which is being tested in combination with bevacizumab in colorectal cancer.

Lonsurf is a fixed-dose oral chemotherapeutic, whereas bevacizumab is a VEGF-targeting antibody, developed and sold under the brand name Avastin by Roche (ROG: SIX).

Servier has been comparing the combo with Avastin plus capecitabine, a rival oral chemotherapy, in the SOLSTICE trial.

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