The leading dopamine agonists, pramipexole (Boehringer Ingelheim’s Mirapex/Mirapexin/Sifrol/BI-Sifrol, generics; Mirapex ER/Mirapexin ER/Sifrol Retard/Mirapex LA) and ropinirole (GlaxoSmithKline’s Requip, generics; GlaxoSmithKline/SkyePharma’s Requip XL/LP/RP/Modutab/Prolib, generics), will continue to garner the most substantial sales among therapies used to treat Parkinson’s disease, according to health care advisory firm Decision Resources.
Additionally, the recent re-entry of UCB’s Neupro/Leganto (rotigotine transdermal system) to the US market (The Pharma Letter July 16), its expanding use in Europe and its forecasted launch in Japan will likewise make it one of the top-selling Parkinson’s disease therapies, owing to its once-daily dosing, convenient transdermal delivery, and premium pricing.
Flat sales to 2021 at just $2.5 billion in major markets
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