Lead HBV candidate dropped after trial death

30 January 2020

East Coast, USA-based Spring Bank Pharmaceuticals (Nasdaq: SBPH) has stopped work on inarigivir soproxil, a Phase II candidate under testing in chronic hepatitis B virus (HBV).

Unexpected serious adverse events in the CATALYST trial, including the death of a patient, were behind the firm’s decision to walk away from the candidate.

Shares in the innovative drugmaker fell by more than a fifth after the announcement was made on Wednesday.

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