Kyowa Hakko Kirin to commercialize Syndax' entinostat in Japan and Korea

8 January 2015

Shares of Japanese mid-size drugmaker Kyowa Hakko Kirin (TYO: 4151) rose 3.55% to 1,138 yen by afternoon trading in Japan, after the company revealed that it has entered into a license agreement with the USA’s privately held Syndax Pharmaceuticals for the exclusive rights to develop and commercialize entinostat in Japan and South Korea.

Entinostat is a Class I selective histone deacetylase (HDAC) inhibitor being developed by Syndax in the USA and Europe in combination with hormone therapy for advanced breast cancer and immune therapy combinations in solid tumors.

Syndax to earn up to $100 million from the deal

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