J&J presents positive new efficacy and safety data for Invokana
Johnson & Johnson (NYSE: JNJ) has unveiled positive Phase III data from the CREDENCE study of Invokana (canagliflozin) at the World Congress of Nephrology in Australia.
The test group achieved a 30% risk reduction for the composite primary endpoint. The trial is comparing Invokana, for which Mundipharma is the exclusive European Union distributor, with placebo in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), when used in addition to standard of care.
The therapy also reduced the risk of secondary cardiovascular (CV) endpoints, including the risk of CV death and hospitalization for heart failure by 31%, major adverse CV events by 20%, and the risk of hospitalization for heart failure alone by 39%.
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