Ionis' olezarsen holds potential to overcome dyslipidemia unmet needs, says analyst

20 October 2023

In September, USA-based Ionis Pharmaceuticals (Nasdaq: IONS) unveiled positive Phase III clinical data for olezarsen, a ligand-conjugated antisense (LICA) designed to inhibit apolipoprotein C-III (apoC-III).

The Phase III studies showed a significant reduction in triglycerides in patients with familial chylomicronemia syndrome (FCS) taking 80mg of olezarsen monthly for six months.

The drug holds the potential to overcome dyslipidemia unmet needs and is expected to reach $849 million in sales by 2032, according to analytics company GlobalData.

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