Innovent’s mazdutide bests Trulicity in Phase III trial

12 September 2024

Innovent Biologics (HKEX: 01801) has announced positive results from a Phase III trial for mazdutide, a dual agonist targeting GLP-1 and glucagon receptor.

The trial, named DREAMS-2, demonstrated that mazdutide outperformed Trulicity (dulaglutide) in both glycemic control and weight reduction in people with type 2 diabetes.

Mazdutide showed significant superiority in lowering HbA1c levels, with reductions of 1.69% and 1.73% at doses of 4 mg and 6 mg, respectively, compared to a 1.36% reduction with dulaglutide.

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