Swedish immunology company InDex Pharmaceuticals InDex Pharmaceuticals has signed a license agreement with the Japanese subsidiary of Viatris (Nasdaq: VTRS) to register and commercialize cobitolimod in Japan for the treatment of ulcerative colitis, under an agreement worth up to $50 million including milestones.
Cobitolimod is a TLR9 agonist which is being evaluated in the global Phase III program CONCLUDE, as a novel treatment for moderate to severe ulcerative colitis.
Under the terms of the agreement, Viatris Japan will pay InDex an upfront fee of $10 million for the exclusive rights to commercialize cobitolimod in Japan. In addition, InDex is eligible for development and sales milestone payments of up to $40 million. Viatris Japan will also pay up to double-digit percentage royalties based on its net sales for the product in Japan.
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