ImmunoGen struck by Phase III trial failure in ovarian cancer

4 March 2019

The value of shares in East Coast, USA-based antibody-drug conjugate (ADC) specialist ImmunoGen (Nasdaq: IMGN) has been halved by news of a Phase III trial miss.

The firm announced on Friday that the FORWARD I trial, which compares the safety and efficacy of mirvetuximab soravtansine with chemotherapy in people with ovarian cancer, did not meet its primary endpoint.

The endpoint of progression-free survival (PFS) was not met in either the entire study population or in the pre-specified subset of patients.

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