Hit and a miss for Marinus in severe seizure trial

18 June 2024

Marinus Pharmaceuticals (Nasdaq: MRNS) has announced topline results showing partial success in the Phase III RAISE trial.

The study is testing the safety and efficacy of intravenous (IV) ganaxolone for treating refractory status epilepticus (RSE), severe and recurring seizures which can be fatal.

Headline data show that one of the co-primary endpoints were met, with 80% of patients in the IV ganaxolone group achieving status epilepticus cessation within 30 minutes.

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