Medicines regulator Health Canada has issued a warning to healthcare professionals on the potential hepatoxicity of Revolade (eltrombopag), a thrombopoietin receptor agonist.
Revolade, also marketed as Promacta in the USA, was acquired by Swiss pharma giant Novartis (NOVN: VX) as part of the three-part asset swap with GlaxoSmithKline (LSE: GSK) which completed in 2015 and involved the Swiss firm acquiring the GSK oncology business for around $16 billion.
The key messages issued by Health Canada are:
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