Health Canada advises on increased risk of hemolysis with serogroup B meningococcal vaccination
Medicines regulator Health Canada has issued a warning saying that an increased risk of hemolysis or low hemoglobin has been observed when patients already being treated with Solaris (eculizumab), from Alexion Pharmaceuticals (Nasdaq: ALXN), were vaccinated against serogroup B meningococcal infection with Bexsero, marketed by GlaxoSmithKline (LSE: GSK).
To minimize the risk of hemolysis when patients who are being treated with Solaris are vaccinated, it is recommended that these patients be vaccinated only after their disease has been controlled and within one week following Solaris infusion, when the Solaris concentration in the blood is considered to be relatively high.
It is recommended that:
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