ERS 2014: GSK reports positive Phase III results of its mepolizumab in asthma
UK pharma major GlaxoSmithKline (LSE: GSK) has reported positive data from its Phase III asthma studies of mepolizumab, an investigational interleukin (IL)-5 antagonist monoclonal antibody.
The drug met its primary endpoints in two studies. The first was a statistically significant reduction in the frequency of clinically significant asthma exacerbations compared to placebo, and the second was a statistically significant reduction of daily oral corticosteroid dose during weeks 20-24 compared to the dose determined during the optimization phase of the trial. The data were presented at the European Respiratory Society (ERS) Congress.
Treatment with mepolizumab also gave improved quality of life and improved asthma control.
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