Grünenthal links up with NovaQuest to advance development of resiniferatoxin

29 March 2022

Family-owned German drugmaker Grünenthal and NovaQuest Capital Management have entered an agreement to advance the global clinical Phase III program of Grünenthal's asset resiniferatoxin (RTX).

The investigational medicine is being developed with the aim of providing patients suffering from pain associated with osteoarthritis with a well-tolerated, non-opioid therapy option that is intended to provide long-lasting pain relief and functional improvement of the affected joints.

RTX is a highly potent transient receptor potential vanilloid 1 (TRPV1) agonist with a well-validated mechanism of action. The Phase III trials will investigate the efficacy, safety and tolerability of RTX in patients with pain associated with osteoarthritis of the knee. The trials will start in 2022 and are designed to meet the requirements for marketing approval in the European Union, the USA, and Japan.

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