GLP-1s show results in alcohol-use disorder

13 February 2025

Danish biopharma giant Novo Nordisk (NOV: N) is breaking new ground with its GLP-1 agonist semaglutide, as a small mid-stage study shows its potential in treating alcohol-use disorder (AUD).

Best known under the brand names Ozempic and Wegovy for diabetes and weight management, the drug was tested against placebo in 48 adults with AUD who were not seeking treatment.

The main finding was that those receiving semaglutide consumed significantly less alcohol during a post-treatment self-administration test, with notable reductions in alcohol craving compared to the placebo group.

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