Full data for cabozantinib against liver cancer published in NEJM
French biotech Ipsen (Euronext: IPN) has published full results from the Phase III CELESTIAL trial of cabozantinib, as a second-line treatment against advanced hepatocellular carcinoma (HCC). Originally presented at ASCO GI in January 2018, the data are now published in the New England Journal of Medicine (NEJM).
The results show that the trial met its primary endpoint, as cabozantinib provided a statistically significant and clinically meaningful improvement in overall survival (OS) versus placebo.
Ipsen and USA-based partner Exelixis (Nasdaq: EXEL) have agreed a collaboration to develop and commercialize the therapy, with Exelixis taking the USA, Takeda Pharmaceutical gaining rights in Japan and Ipsen taking the rest of the world.
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