Fotivda combo fails in earlier treatment setting

19 July 2024

Boston, USA-based AVEO Oncology, a subsidiary of LG Chem (KRX: 051910), has announced that the TiNivo-2 Phase III trial did not meet its primary efficacy endpoint.

The company has been testing Fotivda (tivozanib), a next-generation VEGFR-targeting tyrosine kinase blocker, for people with advanced metastatic renal cell carcinoma (RCC) in the second-line setting.

People in the trial had experienced disease progression after prior treatment with a checkpoint blocker.

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