The US Food and Drug Administration has approved Glyxambi (empagliflozin/linagliptin) tablets from German family-owned drug major Boehringer Ingelheim and Eli Lilly (NYSE: LLY) to improve glycemic control in adults with type 2 diabetes.
The drug has been approved as an adjunct to diet and exercise when empagliflozin and linagliptin are appropriate treatments. It is not recommended in type 1 diabetes patients or for the treatment of diabetic ketoacidosis, and has not been studied in patients with a history of pancreatitis, and it is unknown if using Glyxambi increases risk of pancreatitis in these patients.
It combines the dual mechanisms of action of a sodium glucose co-transporter-2 inhebitor and a dipeptidyl peptidase-4 inhibitor in a once-daily tablet taken in the morning.
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