FDA adcom narrowly backs terlipressin for HRS-1

16 July 2020

Good news on the regulatory progress of its terlipressin pushed shares of Mallinckrodt (NYSE: MNK) up 12.7% by close of trading on Wednesday, plus a further 5.8% to $3.28 in after-hours trading.

UK-headquartered drugmaker announced that the Cardiovascular and Renal Drugs Advisory Committee of the US Food and Drug Administration voted to recommend approval for its investigational agent terlipressin to treat adults with hepatorenal syndrome type 1 (HRS-1) (8 yes; 7 no).

HRS-1 is an acute and life-threatening syndrome involving acute kidney failure in people with cirrhosis. Terlipressin is an investigational agent being evaluated for the treatment of HRS-1 in the USA, and its safety and effectiveness have not yet been established by the FDA.

This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Try before you buy

Free

7 day trial access

Take a Free Trial

All the news that moves the needle in pharma and biotech
Exclusive features, podcasts, interviews, data analyses and commentary from our global network of life sciences reporters.
Receive The Pharma Letter daily news bulletin, free forever.

Become a subscriber

£820

Or £77 per month

Subscribe Now

Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
Daily roundup of key events in pharma and biotech.
Monthly in-depth briefings on Boardroom appointments and M&A news.
Choose from a cost-effective annual package or a flexible monthly subscription

The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK